Induced pluripotent stem (iPS) cells can be obtained by reprogramming somatic cells through expression of key transcription factors. This set of lentivirus contains four genes commonly used for iPS cell generation: SOX2 (Cat. LV-1267), OCT3/4 (Cat. LV-1265), KLF4 (Cat. LV-1263) and C-MYC (Cat. LV-1261). All of these four genes are driven by the EF1a promoter with puromycin as a selection marker. This highly purified lentivirus set is ready-to-use for iPS cell generation.