RPMI-1788/RFP cells are derived from the human B lymphocyte RPMI-1788 cell line by stably integration of a constitutive RFP stably expression construct. RPMI-1788 cells have been used in cancer research and drug development. RPMI-1788/RFP cells stably stably express RFP, can be used for in vitro assays and in vivo imaging.