Panc 10.05/RFP-Luciferase cells are derived from the human pancreas adenocarcinoma Panc 10.05 cell line by stably integration of a constitutive RFP-Firefly luciferase stably expression construct. Panc 10.05 cells have been used in research to study the biology of pancreatic cancer, including tumor growth, metastasis, and responses to various therapies. Panc 10.05/RFP-Luciferse cells stably stably express RFP and Firefly luciferase, can be used for in vitro assays and in vivo imaging.