MV4-11/Cre cells are derived from the human MV4-11 macrophage cell line by stably integration of a constitutive Cre recombinase stably expression construct. MV4-11 cell line was generated from biphenotypic B myelomonocytic leukemia, has been widely used in cancer research and drug development. MV4-11/Cre cells stably express a nuclear localized Cre recombinase.