MOLM-13/iRFP cells are derived from the human leukemia cell line MOLM-13 by stably integration of a constitutive miRFP670 stably expression construct. The MOLM-13 cell line is a widely used human acute myeloid leukemia (AML) model, particularly classified as FAB M5a (acute monocytic leukemia), has been widely used in AML research, especially when investigating mechanisms related to MLL gene rearrangements and FLT3-ITD mutations. MOLM-13/iRFP cells stably stably express miRFP670, can be used for in vitro assays and in vivo imaging.