Lentiviral human XPA sgRNA gene knockout kit

Catalog number

HKO-625857

Kit Components

Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

To order

HKO-625857-25
Lentiviral human XPA sgRNA gene knockout kit (25)
Lentiviral particles for a set of three sgRNAs mixture (10^8 TU/ml, 25 ul), and a pair of Indel screening PCR primers (100 reactions)
$499.00
HKO-625857-100
Lentiviral human XPA sgRNA gene knockout kit (100)
Lentiviral particles for a set of three sgRNAs mixture (10^8 TU/ml, 100 ul), and a pair of Indel screening PCR primers (200 reactions)
$890.00
HKO-625857-10ug
Lentiviral human XPA sgRNA gene knockout kit (plasmid)
Lentiviral plasmids for a set of three sgRNAs (10ug each), and a pair of Indel screening PCR primers (200 reactions)
$890.00

Gene symbol	XPA
Synonyms	XP1 XPAC
Species	HUMAN
Gene ID	7507
Summary	This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017].
NM numbers targeted (Accession number:Exon:CDS Fragment)	NM_000380

Functional titer	1x10^8 TU/ml
Titration method	counting puromycin resistant cell clones
Purity	In vivo grade
Pseudotype	VSVG
Storage buffer	LentiShield™ lentivirus storage buffer
Storage condition	-80°C
Availability	3-5 weeks

Target sgRNA	Human XPA sgRNA
Promoter for target sgRNA	U6
Mammalian selection	puromycin
Promoter for mammalian selection gene	EF1a
E.coli selection	Amp
Storage condition	-20°C
Availability	1-2 weeks