Lentiviral human SIGLEC12 shRNA (Synapsin)

Catalog number
HSH-925080
Kit Components
Lentiviral particles or plasmids for 3 unique target specific shRNA and 1 scramble shRNA, RT-PCR primer mix for target specific gene and a housekeeping gene

To order

  1. HSH-925080-25

    Lentiviral human SIGLEC12 shRNA (Synapsin) (25)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, 25 ul each, functional titer of 1x10^8 TU/ml
    $1,190.00
  2. HSH-925080-100

    Lentiviral human SIGLEC12 shRNA (Synapsin) (100)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, 4x25 ul each, functional titer of 1x10^8 TU/ml
    $2,690.00
  3. HSH-925080-10ug

    Lentiviral human SIGLEC12 shRNA (Synapsin) plasmid

    Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, 10 ug each
    $1,490.00
  4. HSH-925080-25GFP

    Lentiviral human SIGLEC12 shRNA (Synapsin,GFP) (25)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, with a GFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
    $1,190.00
  5. HSH-925080-100GFP

    Lentiviral human SIGLEC12 shRNA (Synapsin,GFP) (100)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, with a GFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
    $2,690.00
  6. HSH-925080-10ugGFP

    Lentiviral human SIGLEC12 shRNA (Synapsin,GFP) plasmid

    Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, with a GFP reporter, 10 ug each
    $1,490.00
  7. HSH-925080-25RFP

    Lentiviral human SIGLEC12 shRNA (Synapsin,RFP) (25)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, with a RFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
    $1,190.00
  8. HSH-925080-100RFP

    Lentiviral human SIGLEC12 shRNA (Synapsin,RFP) (100)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, with a RFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
    $2,690.00
  9. HSH-925080-10ugRFP

    Lentiviral human SIGLEC12 shRNA (Synapsin,RFP) plasmid

    Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, with a RFP reporter, 10 ug each
    $1,490.00
  10. HSH-925080-25iRFP

    Lentiviral human SIGLEC12 shRNA (Synapsin,iRFP) (25)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, with a miRFP670 reporter, 25 ul each, functional titer of 1x10^8 TU/ml
    $1,190.00
  11. HSH-925080-100iRFP

    Lentiviral human SIGLEC12 shRNA (Synapsin,iRFP) (100)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, with a miRFP670 reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
    $2,690.00
  12. HSH-925080-10ugiRFP

    Lentiviral human SIGLEC12 shRNA (Synapsin,iRFP) plasmid

    Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the human synapsin 1 gene promoter, with a miRFP670 reporter, 10 ug each
    $1,490.00

Product Details

Target gene information

Gene symbolSIGLEC12
SynonymsS2V Siglec-XII SIGLECL1 SLG
Specieshuman
Gene ID89858
SummarySialic acid-binding immunoglobulin-like lectins (SIGLECs) are a family of cell surface proteins belonging to the immunoglobulin superfamily. They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins. This gene encodes a member of the SIGLEC3-like subfamily of SIGLECs. Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains, and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like. The encoded protein, upon tyrosine phosphorylation, has been shown to recruit the Src homology 2 domain-containing protein-tyrosine phosphatases SHP1 and SHP2. It has been suggested that the protein is involved in the negative regulation of macrophage signaling by functioning as an inhibitory receptor. This gene is located in a cluster with other SIGLEC3-like genes on 19q13.4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013].

shRNA lentiviral particle information

Functional titer1x10^8 TU/ml
Titration methodcounting puromycin resistant cell clones
PurityIn vivo grade
PseudotypeVSV-G
Storage bufferLentiShield"Lentivirus storage buffer
Storage condition-80°C
Availability3-4 weeks

shRNA lentiviral plasmid information

Target shRNAHuman SIGLEC12 shRNA
Promoter for target shRNAhuman synapsin 15080
Mammalian selectionPuromycin
Promoter for mammalian selection genePGK
E.coli selectionAmp
Storage condition-20°C
Availability1-2 weeks
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