Lentiviral particles or plasmids for 3 unique target specific shRNA and 1 scramble shRNA, RT-PCR primer mix for target specific gene and a housekeeping gene
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the UAS promoter, 25 ul each, functional titer of 1x10^8 TU/ml
$890.00
HSH-118712-100
Lentiviral human SHC1 shRNA (UAS) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the UAS promoter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$1,980.00
HSH-118712-10ug
Lentiviral human SHC1 shRNA (UAS) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet promoter, 10 ug each
$1,190.00
Product Details
Target gene information
Gene symbol
SHC1
Synonyms
SHC SHCA
Species
human
Gene ID
6464
Summary
This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
shRNA lentiviral particle information
Functional titer
1x10^8 TU/ml
Titration method
counting puromycin resistant cell clones
Purity
N/A
Pseudotype
N/A
Storage buffer
LentiShield™Lentivirus storage buffer
Storage condition
-80°C
Availability
3-4 weeks
shRNA lentiviral plasmid information
Target shRNA
Human SHC1 shRNA
Promoter for target shRNA
UAS
Mammalian selection
Puromycin
Promoter for mammalian selection gene
PGK
E.coli selection
Amp
Storage condition
-20°C
Availability
1-2 weeks
Lentiviral shRNA Gene Knockdown and Verification Kit
