Lentiviral particles or plasmids for 3 unique target specific shRNA and 1 scramble shRNA, RT-PCR primer mix for target specific gene and a housekeeping gene
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-219138-100
Lentiviral human SGO1 shRNA (UBC) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-219138-10ug
Lentiviral human SGO1 shRNA (UBC) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, 10 ug each
$1,290.00
HSH-219138-25GFP
Lentiviral human SGO1 shRNA (UBC,GFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, with a GFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-219138-100GFP
Lentiviral human SGO1 shRNA (UBC,GFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, with a GFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-219138-10ugGFP
Lentiviral human SGO1 shRNA (UBC,GFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, with a GFP reporter, 10 ug each
$1,290.00
HSH-219138-25RFP
Lentiviral human SGO1 shRNA (UBC,RFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, with a RFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-219138-100RFP
Lentiviral human SGO1 shRNA (UBC,RFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, with a RFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-219138-10ugRFP
Lentiviral human SGO1 shRNA (UBC,RFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, with a RFP reporter, 10 ug each
$1,290.00
HSH-219138-25iRFP
Lentiviral human SGO1 shRNA (UBC,iRFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, with a miRFP670 reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-219138-100iRFP
Lentiviral human SGO1 shRNA (UBC,iRFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, with a miRFP670 reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-219138-10ugiRFP
Lentiviral human SGO1 shRNA (UBC,iRFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the UBC promoter, with a miRFP670 reporter, 10 ug each
$1,290.00
Product Details
Target gene information
Gene symbol
SGO1
Synonyms
CAID NY-BR-85 SGO SGOL1
Species
human
Gene ID
151648
Summary
The protein encoded by this gene is a member of the shugoshin family of proteins. This protein is thought to protect centromeric cohesin from cleavage during mitotic prophase by preventing phosphorylation of a cohesin subunit. Reduced expression of this gene leads to the premature loss of centromeric cohesion, mis-segregation of sister chromatids, and mitotic arrest. Evidence suggests that this protein also protects a small subset of cohesin found along the length of the chromosome arms during mitotic prophase. An isoform lacking exon 6 has been shown to play a role in the cohesion of centrioles (PMID: 16582621 and PMID:18331714). Mutations in this gene have been associated with Chronic Atrial and Intestinal Dysrhythmia (CAID) syndrome, characterized by the co-occurrence of Sick Sinus Syndrome (SSS) and Chronic Intestinal Pseudo-obstruction (CIPO) within the first four decades of life (PMID:25282101). Fibroblast cells from CAID patients exhibited both increased cell proliferation and higher rates of senescence. Pseudogenes of this gene have been found on chromosomes 1 and 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015].
