Lentiviral particles or plasmids for 3 unique target specific shRNA and 1 scramble shRNA, RT-PCR primer mix for target specific gene and a housekeeping gene
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, 25 ul each, functional titer of 1x10^8 TU/ml
$1,190.00
HSH-820063-100
Lentiviral human OAZ2 shRNA (tet) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,690.00
HSH-820063-10ug
Lentiviral human OAZ2 shRNA (tet) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, 10 ug each
$1,490.00
HSH-820063-25GFP
Lentiviral human OAZ2 shRNA (tet,GFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a GFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$1,190.00
HSH-820063-100GFP
Lentiviral human OAZ2 shRNA (tet,GFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a GFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,690.00
HSH-820063-10ugGFP
Lentiviral human OAZ2 shRNA (tet,GFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a GFP reporter, 10 ug each
$1,490.00
HSH-820063-25RFP
Lentiviral human OAZ2 shRNA (tet,RFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a RFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$1,190.00
HSH-820063-100RFP
Lentiviral human OAZ2 shRNA (tet,RFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a RFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,690.00
HSH-820063-10ugRFP
Lentiviral human OAZ2 shRNA (tet,RFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a RFP reporter, 10 ug each
$1,490.00
HSH-820063-25iRFP
Lentiviral human OAZ2 shRNA (tet,iRFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a miRFP670 reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$1,190.00
HSH-820063-100iRFP
Lentiviral human OAZ2 shRNA (tet,iRFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a miRFP670 reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,690.00
HSH-820063-10ugiRFP
Lentiviral human OAZ2 shRNA (tet,iRFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a miRFP670 reporter, 10 ug each
$1,490.00
Product Details
Target gene information
Gene symbol
OAZ2
Synonyms
AZ2
Species
human
Gene ID
4947
Summary
The protein encoded by this gene belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamines. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto-regulatory circuit. This gene encodes antizyme 2, the second member of the antizyme family. Like antizyme 1, antizyme 2 has broad tissue distribution, inhibits ODC activity and polyamine uptake, and stimulates ODC degradation in vivo; however, it fails to promote ODC degradation in vitro. Antizyme 2 is expressed at lower levels than antizyme 1, but is evolutionary more conserved, suggesting it likely has an important biological role. Studies also show different subcellular localization of antizymes 1 and 2, indicating specific function for each antizyme in discrete compartments of the cell. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2014].
