To order
Product Details
Target gene information
| Gene symbol | NRP1 |
| Synonyms | BDCA4 CD304 NP1 NRP VEGF165R |
| Species | human |
| Gene ID | 8829 |
| Summary | This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011]. |
shRNA lentiviral particle information
| Functional titer | 1x10^8 TU/ml |
| Titration method | counting puromycin resistant cell clones |
| Purity | In vivo grade |
| Pseudotype | VSV-G |
| Storage buffer | LentiShield™Lentivirus storage buffer |
| Storage condition | -80°C |
| Availability | 3-4 weeks |
shRNA lentiviral plasmid information
| Target shRNA | Human NRP1 shRNA |
| Promoter for target shRNA | UBC |
| Mammalian selection | Puromycin |
| Promoter for mammalian selection gene | PGK |
| E.coli selection | Amp |
| Storage condition | -20°C |
| Availability | 1-2 weeks |