Lentiviral human JAK3 sgRNA gene knockout kit

Catalog number

HKO-614430

Kit Components

Lentiviral particles or plasmids for a set of three sgRNAs, and a pair of Indel screening PCR primers

To order

HKO-614430-25
Lentiviral human JAK3 sgRNA gene knockout kit (25)
Lentiviral particles for a set of three sgRNAs mixture (10^8 TU/ml, 25 ul), and a pair of Indel screening PCR primers (100 reactions)
$499.00
HKO-614430-100
Lentiviral human JAK3 sgRNA gene knockout kit (100)
Lentiviral particles for a set of three sgRNAs mixture (10^8 TU/ml, 100 ul), and a pair of Indel screening PCR primers (200 reactions)
$890.00
HKO-614430-10ug
Lentiviral human JAK3 sgRNA gene knockout kit (plasmid)
Lentiviral plasmids for a set of three sgRNAs (10ug each), and a pair of Indel screening PCR primers (200 reactions)
$890.00

Gene symbol	JAK3
Synonyms	JAK-3 JAK3_HUMAN JAKL L-JAK LJAK
Species	HUMAN
Gene ID	3718
Summary	The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008].
NM numbers targeted (Accession number:Exon:CDS Fragment)	NM_000215:6:5

Functional titer	1x10^8 TU/ml
Titration method	counting puromycin resistant cell clones
Purity	In vivo grade
Pseudotype	VSV-G
Storage buffer	LentiShield™Lentivirus storage buffer
Storage condition	-80°C
Availability	3-5 weeks

Target sgRNA	Human JAK3 gRNA
Promoter for target sgRNA	U6
Mammalian selection	puromycin
Promoter for mammalian selection gene	EF1a
E.coli selection	Amp
Storage condition	-20°C
Availability	1-2 weeks