Lentiviral particles or plasmids for 3 unique target specific shRNA and 1 scramble shRNA, RT-PCR primer mix for target specific gene and a housekeeping gene
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-611353-100
Lentiviral human ESRRG shRNA (CAG) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-611353-10ug
Lentiviral human ESRRG shRNA (CAG) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, 10 ug each
$1,290.00
HSH-611353-25GFP
Lentiviral human ESRRG shRNA (CAG,GFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, with a GFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-611353-100GFP
Lentiviral human ESRRG shRNA (CAG,GFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, with a GFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-611353-10ugGFP
Lentiviral human ESRRG shRNA (CAG,GFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, with a GFP reporter, 10 ug each
$1,290.00
HSH-611353-25RFP
Lentiviral human ESRRG shRNA (CAG,RFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, with a RFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-611353-100RFP
Lentiviral human ESRRG shRNA (CAG,RFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, with a RFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-611353-10ugRFP
Lentiviral human ESRRG shRNA (CAG,RFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, with a RFP reporter, 10 ug each
$1,290.00
HSH-611353-25iRFP
Lentiviral human ESRRG shRNA (CAG,iRFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, with a miRFP670 reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-611353-100iRFP
Lentiviral human ESRRG shRNA (CAG,iRFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, with a miRFP670 reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-611353-10ugiRFP
Lentiviral human ESRRG shRNA (CAG,iRFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the CAG promoter, with a miRFP670 reporter, 10 ug each
$1,290.00
Product Details
Target gene information
Gene symbol
ESRRG
Synonyms
ERR-gamma ERR3 ERRg ERRgamma NR3B3
Species
human
Gene ID
2104
Summary
This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region. [provided by RefSeq, Aug 2011].
