Lentiviral particles or plasmids for 3 unique target specific shRNA and 1 scramble shRNA, RT-PCR primer mix for target specific gene and a housekeeping gene
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-522160-100
Lentiviral human CD274 shRNA (CMV) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-522160-10ug
Lentiviral human CD274 shRNA (CMV) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, 10 ug each
$1,290.00
HSH-522160-25GFP
Lentiviral human CD274 shRNA (CMV,GFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, with a GFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-522160-100GFP
Lentiviral human CD274 shRNA (CMV,GFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, with a GFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-522160-10ugGFP
Lentiviral human CD274 shRNA (CMV,GFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, with a GFP reporter, 10 ug each
$1,290.00
HSH-522160-25RFP
Lentiviral human CD274 shRNA (CMV,RFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, with a RFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-522160-100RFP
Lentiviral human CD274 shRNA (CMV,RFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, with a RFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-522160-10ugRFP
Lentiviral human CD274 shRNA (CMV,RFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, with a RFP reporter, 10 ug each
$1,290.00
HSH-522160-25iRFP
Lentiviral human CD274 shRNA (CMV,iRFP) (25)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, with a miRFP670 reporter, 25 ul each, functional titer of 1x10^8 TU/ml
$980.00
HSH-522160-100iRFP
Lentiviral human CD274 shRNA (CMV,iRFP) (100)
Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, with a miRFP670 reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
$2,190.00
HSH-522160-10ugiRFP
Lentiviral human CD274 shRNA (CMV,iRFP) plasmid
Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the CMV promoter, with a miRFP670 reporter, 10 ug each
$1,290.00
Product Details
Target gene information
Gene symbol
CD274
Synonyms
B7-H B7H1 hPD-L1 PD-L1 PDCD1L1 PDCD1LG1 PDL1
Species
human
Gene ID
29126
Summary
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015].
