Lentiviral human ADD3 shRNA (tet)

Catalog number
HSH-818295
Kit Components
Lentiviral particles or plasmids for 3 unique target specific shRNA and 1 scramble shRNA, RT-PCR primer mix for target specific gene and a housekeeping gene

To order

  1. HSH-818295-25

    Lentiviral human ADD3 shRNA (tet) (25)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, 25 ul each, functional titer of 1x10^8 TU/ml
    $1,190.00
  2. HSH-818295-100

    Lentiviral human ADD3 shRNA (tet) (100)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, 4x25 ul each, functional titer of 1x10^8 TU/ml
    $2,690.00
  3. HSH-818295-10ug

    Lentiviral human ADD3 shRNA (tet) plasmid

    Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, 10 ug each
    $1,490.00
  4. HSH-818295-25GFP

    Lentiviral human ADD3 shRNA (tet,GFP) (25)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a GFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
    $1,190.00
  5. HSH-818295-100GFP

    Lentiviral human ADD3 shRNA (tet,GFP) (100)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a GFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
    $2,690.00
  6. HSH-818295-10ugGFP

    Lentiviral human ADD3 shRNA (tet,GFP) plasmid

    Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a GFP reporter, 10 ug each
    $1,490.00
  7. HSH-818295-25RFP

    Lentiviral human ADD3 shRNA (tet,RFP) (25)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a RFP reporter, 25 ul each, functional titer of 1x10^8 TU/ml
    $1,190.00
  8. HSH-818295-100RFP

    Lentiviral human ADD3 shRNA (tet,RFP) (100)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a RFP reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
    $2,690.00
  9. HSH-818295-10ugRFP

    Lentiviral human ADD3 shRNA (tet,RFP) plasmid

    Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a RFP reporter, 10 ug each
    $1,490.00
  10. HSH-818295-25iRFP

    Lentiviral human ADD3 shRNA (tet,iRFP) (25)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a miRFP670 reporter, 25 ul each, functional titer of 1x10^8 TU/ml
    $1,190.00
  11. HSH-818295-100iRFP

    Lentiviral human ADD3 shRNA (tet,iRFP) (100)

    Lentiviral particles for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a miRFP670 reporter, 4x25 ul each, functional titer of 1x10^8 TU/ml
    $2,690.00
  12. HSH-818295-10ugiRFP

    Lentiviral human ADD3 shRNA (tet,iRFP) plasmid

    Lentiviral constructs for 3 unique target specific shRNA and 1 scramble shRNA driven by the tet-inducible promoter, with a miRFP670 reporter, 10 ug each
    $1,490.00

Product Details

Target gene information

Gene symbolADD3
SynonymsADDL CPSQ3
Specieshuman
Gene ID120
SummaryAdducins are heteromeric proteins composed of different subunits referred to as adducin alpha, beta and gamma. The three subunits are encoded by distinct genes and belong to a family of membrane skeletal proteins involved in the assembly of spectrin-actin network in erythrocytes and at sites of cell-cell contact in epithelial tissues. While adducins alpha and gamma are ubiquitously expressed, the expression of adducin beta is restricted to brain and hematopoietic tissues. Adducin, originally purified from human erythrocytes, was found to be a heterodimer of adducins alpha and beta. Polymorphisms resulting in amino acid substitutions in these two subunits have been associated with the regulation of blood pressure in an animal model of hypertension. Heterodimers consisting of alpha and gamma subunits have also been described. Structurally, each subunit is comprised of two distinct domains. The amino-terminal region is protease resistant and globular in shape, while the carboxy-terminal region is protease sensitive. The latter contains multiple phosphorylation sites for protein kinase C, the binding site for calmodulin, and is required for association with spectrin and actin. Alternatively spliced adducin gamma transcripts encoding different isoforms have been described. The functions of the different isoforms are not known. [provided by RefSeq, Jul 2008].

shRNA lentiviral particle information

Functional titer1x10^8 TU/ml
Titration methodcounting puromycin resistant cell clones
PurityIn vivo grade
PseudotypeVSV-G
Storage bufferLentiShield™Lentivirus storage buffer
Storage condition-80°C
Availability3-4 weeks

shRNA lentiviral plasmid information

Target shRNAHuman ADD3 shRNA
Promoter for target shRNATetracycline response element (TRE)
Mammalian selectionPuromycin
Promoter for mammalian selection genePGK
E.coli selectionAmp
Storage condition-20°C
Availability1-2 weeks
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