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$2,980.00

KCL22-r/Cre stable cell line

Catalog number
CL-2104
Description
KCL22-r/Cre cells are derived from human lymphoblast-like cell line KCL22-r by stably integration of a constitutive Cre recombinase stably expression construct. KCL22-r cells are a variant of the KCL22 cell line that is specifically used to study resistance to imatinib, a tyrosine kinase inhibitor commonly used to treat chronic myeloid leukemia (CML). Imatinib targets the BCR-ABL fusion protein, which is a key driver of CML. The paired KCL22-s and KCL22-r clones are useful cell line models of sensitivity and resistance to imatinib. KCL22-r/Cre cells stably express a nuclear localized Cre recombinase.
KCL22-r/Cre stable cell line
Product Details

Product Details

Package Size 2 x 10^6 cells
Parental cell line KCL22-r cells
Transgenic gene Cre recombinase
Mammalian selection Puromycin
Biosafety level 2
Storage Liquid nitrogen
Availability 3-4 weeks
Shipping condition dry ice

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