Jurkat/STAT3 Reporter (Luc) cells are derived from the human immortalized T lymphocyte Jurkat cell line by stably integration of a STAT3 firefly luciferase reporter construct. Jurkat cells have been used to study acute T cell leukemia, T cell signaling, and the of various chemokine receptors susceptible to viral entry, particularly HIV. Jurkat/STAT3 Reporter (Luc) cells stably express firefly luciferase under the control of the STAT3 response elements, can be used for monitoring the activity of STAT3 signaling pathway.
