Overview
The serine protease TMPRSS2 plays a crucial role in SARS-CoV-2 pathogenesis by cleaving the viral S glycoprotein and facilitating viral activation. It has been reported a TMPRSS2 inhibitor approved for clinical use blocked SARS-CoV-2 entry.
Product Details
| Vector name | pLV-CMV-TMPRSS2-PGK-Hyg |
| Package Size | 10 ug |
| E.coli selection | Amp |
| Target Gene | Human TMPRSS2 isoform 2 (NM_005656.4) |
| Promoter for target gene | CMV |
| Mammalian selection | Hygromycin |
| Promoter for selection gene | PGK |
| Storage | -20°C |
| Availability | In stock |