This gene encodes a protein that functions as an assembly component of multiple structure-specific endonucleases. These endonuclease complexes are required for repair of specific types of DNA lesions and critical for cellular responses to replication fork failure. Mutations in this gene were found in patients with Fanconi anemia. [provided by RefSeq, Sep 2016].
Knockout cell line information
Deliverables
One vial of gene knockout cells (1x10^6 cells) and one vial of control parental cells (1x10^6)