$4,980.00

Human SLCO1C1 Knockout A549 cell line

Catalog number
A549KO-18607
Description
Engineered clonal A549 cells with SLCO1C1 gene knockout, sequence confirmed.

Product Details

Target gene information

Gene symbolSLCO1C1
SynonymsOATP-F OATP1 OATP14 OATP1C1 OATPF OATPRP5 SLC21A14
SpeciesHUMAN
Gene ID53919
SummaryThis gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2009].

Knockout cell line information

DeliverablesOne vial of gene knockout cells (1x10^6 cells) and one vial of control parental cells (1x10^6)
Parental cell lineA549
GenotypeSLCO1C1-/-
ValidationSanger Sequencing
Mammalian selectionN/A
Biosafety level2
StorageLiquid nitrogen
Availabilityapproximately 12 weeks
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