The protein encoded by this gene is a serine/threonine protein kinase required for normal entry into replicative senescence. The encoded protein also is involved in cell cycle arrest in response to double-stranded DNA damage. Finally, this protein plays a role in maintaining cilium integrity, and defects in this gene have been associated with ciliopathies. [provided by RefSeq, Jan 2017].
Knockout cell line information
Deliverables
One vial of gene knockout cells (1x10^6 cells) and one vial of control parental cells (1x10^6)
