$4,980.00

Human EYA3 Knockout HEK293T cell line

Catalog number
293TKO-12911
Description
Engineered clonal HEK293T cells with EYA3 gene knockout, sequence confirmed.

Product Details

Target gene information

Gene symbol
EYA3
Species
HUMAN
Gene ID
2140
Summary
This gene encodes a member of the eyes absent (EYA) family of proteins. The encoded protein may act as a transcriptional activator and have a role during development. It can act as a mediator of chemoresistance and cell survival in Ewing sarcoma cells, where this gene is up-regulated via a micro-RNA that binds to the 3' UTR of the transcript. A similar protein in mice acts as a transcriptional activator. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2013].

Knockout cell line information

Deliverables
One vial of gene knockout cells (1x10^6 cells) and one vial of control parental cells (1x10^6)
Parental cell line
HEK293T
Genotype
EYA3-/-
Validation
Sanger sequencing
Biosafety level
2
Storage
Liquid nitrogen
Availability
approximately 12 weeks
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