The protein encoded by this gene regulates the DNA damage response through several different signaling pathways. One such pathway is the p53-HDM2-p21(WAF1) pathway, which is critical to the DNA damage response. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015].
Knockout cell line information
Deliverables
One vial of gene knockout cells (1x10^6 cells) and one vial of control parental cells (1x10^6)
