$4,980.00

Human AXL Knockout A549 cell line

Catalog number
A549KO-10794
Description
Engineered clonal A549 cells with AXL gene knockout, sequence confirmed.

Product Details

Target gene information

Gene symbolAXL
SynonymsARK JTK11 Tyro7 UFO
SpeciesHUMAN
Gene ID558
SummaryThe protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013].

Knockout cell line information

DeliverablesOne vial of gene knockout cells (1x10^6 cells) and one vial of control parental cells (1x10^6)
Parental cell lineA549
GenotypeAXL-/-
ValidationSanger Sequencing
Mammalian selectionN/A
Biosafety level2
StorageLiquid nitrogen
Availabilityapproximately 12 weeks
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