HH/GFP-luciferase cells are derived from the human human T lymphoblast HH cell line by stably integration of a constitutive GFP and Firefly luciferase stably expression construct. The HH cell line has been widely used in immuno-oncology and immunology studies. HH/GFP-luciferase cells stably express GFP and Firefly luciferase, can be used for in vitro assays and in vivo imaging.