HepG2/Cre cells are derived from the human hepatocarcinoma HepG2 cell line by stably integration of a constitutive Cre recombinase stably expression construct. The HepG2 cell line has been widely used as a model system in biomedical research, particularly in studies related to liver biology, drug metabolism, toxicology, hepatitis virus infection and liver cancer. HepG2/Cre cells stably express a nuclear localized Cre recombinase.
