BRN2 (also known as POU3F2) encodes a member of the POU-III class of neural transcription factors. The encoded protein is involved in neuronal differentiation and enhances the activation of corticotropin-releasing hormone regulated genes. BRN2 lentivirus (TET-inducible, Puro) expresses human BRN2 under the control of the Tet responsive promoter, with puromycin as a selection marker.