A549/IFN beta reporter (GFP) cells are derived from the human A549 lung carcinoma cell line by stably integration of a IFN beta GFP reporter construct. A549 cell line has been widely used in cancer research, immunological studies and drug development. A549/IFN beta reporter (GFP) cells stably express GFP under the control of the INF beta promter, can be used for monitoring the activity of IFN beta signaling pathway.
Interferons (IFNs) are pleiotropic cytokines that plays important roles in variety of biologic activities, including innate and adaptive immune responses, organogenesis and tumor development. This A549/IFN beta Reporter (GFP) cell line expresses eGFP under the control of IFN beta promoter, can be used to monitor the regulation of IFN beta expression.
